MBV3040 ¨C Biochemistry of the nucleic acids

Course description

• Course content
• Learning outcome
• Admission
• Prerequisites

• Teaching
• Examination
• Evaluation

Course content

Nucleotide metabolism. DNA and RNA structure. Chromatin structure, DNA methylation, histone modification. DNA replication and repair. RNA transcription, processing of mRNA, regulation of gene activity

Learning outcome

Knowledge if how nucleotides are synthesized and degraded in cells. An understanding of structure-function relationships for nucleic acids and chromatin. Knowledge of the enzymatic basis of replication of and error correction in the genome. An understanding of how genes are read and how the transcribed RNA is processed, and how genes are regulated through a coordinated collaboration between proteins and nucleic acid sequences. Critical reading of scientific papers and presentation of these.

Admission

Students who are admitted to study programmes at UiO must each semester register which courses and exams they wish to sign up for in Studentweb.

If you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures.

Prerequisites

Formal prerequisite knowledge

In addition to fulfilling the Higher Education Entrance Qualification, applicants have to meet the following special admission requirements:

• Mathematics R1 (or Mathematics S1 and S2) + R2

And in addition one of these:

• Physics (1+2)
• Chemistry (1+2)
• Biology (1+2)
• Information technology (1+2)
• Geosciences (1+2)
• Technology and theories of research (1+2)

The special admission requirements may also be covered by equivalent studies from Norwegian upper secondary school or by other equivalent studies (in Norwegian).

MBV1030 ¨C General biochemistry (discontinued) and MBV2010 ¨C Molecular biology (continued) or corresponding, from 2008.

Recommended previous knowledge

MBV1030 ¨C General biochemistry (discontinued) and MBV2010 ¨C Molecular biology (continued). Prerequisites from 2008.

Teaching

Lectures (30 hours), colloquia (15 hours). Student presentation of scientific papers (ca 5 hours). The colloquia and presentations are compulsory. The colloquia and presentations must be approved before the exam.

Examination

Midt term exam, 1,5 hours, in March (counts ca 25%). Allowed examination aids: None. Students with valid grounds for absence, sickness, shall be offered a deferred examination within approximately 3 weeks after the mid-term exam.

The presentation of scientific papers (counts ca 25%)

Final written exam, 3 hours, in June (counts ca 50%). Allowed examination aids: None. Letter grading.

This subject offer new examination in the beginning of the subsequent term for candidates who withdraw during an ordinary examination or fail an ordinary examination. More information about new examination can be found on the faculty's site.

Evaluation

The course is subject to continuous evaluation. At regular intervals we also ask students to participate in a more comprehensive evaluation.