FARM1130 – Pharmaceutically Based Organic Chemistry
Course description
Course content
This course will provide students in pharmacy a solid foundation in organic chemistry where relevant pharmaceutical topics will be applied to illustrate organic chemistry. The course will also give the students the necessary knowledge to participate and understand the pharmacy curriculum in later courses, such as biochemistry, medicinal chemistry, pharmacognosy, drug analysis and pharmaceutics. In this course examples from medicinal chemistry and pharmacognosy will be used to acquire knowledge in organic chemistry.
Learning outcome
After completing the course:
- You will have knowledge of conformational analysis and stereochemistry and can apply this knowledge to assess the stereochemical aspects of active ingredients and natural products.
- You can apply reaction mechanisms to explain key organic chemical reactions, with a focus on elimination reactions, electrophilic aromatic substitution reactions, carbonyl-based reactions, and condensation reactions.
- You will have knowledge of aromatic compounds, aliphatic and aromatic heterocyclic compounds, and can elaborate on the most central reactions and chemical properties of these compounds.
- You will have knowledge of the pharmaceutically most relevant substitution reactions, nucleophilic addition reactions, and oxidation/reduction reactions, and can apply this knowledge to theoretical issues.
- You will have knowledge of central spectroscopic methods for structural elucidation of active ingredients and natural products and can apply these methods to identify simple organic compounds based on their spectroscopic data.
- You will be able to use organic chemistry laboratory techniques relevant to pharmacy to synthesize simple active ingredients, as well as analyse and interpret the results.??
Admission to the course
The course is only available to students enrolled at the Department of Pharmacy at the University of Oslo.
Pregnant and breastfeeding:?For safety reasons, pregnant and breastfeeding women cannot participate in laboratory exercises in this course. This is due to the use of chemicals in the laboratory exercises that may be harmful to the fetus or child. No exemptions or accommodations for the laboratory exercises will be granted, as these must be completed and approved to fulfill the learning outcomes of the course. Students affected by this should contact the Study administration at the Department of Pharmacy?for more information.
Formal prerequisite knowledge
- Approved the compulsory parts of FARM1100 – Pharmaceutical Chemistry
- Passed the compulsory HSE courses HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety required for students at the 5-year Master`s Programme in Pharmacy.
Course exemption: Laws and regulations describing the overall learning outcome regulate the Pharmacy Programme. Exemptions are only granted if all learning outcomes of the course are covered.?
Recommended previous knowledge
Overlapping courses
- 9 credits overlap with FRM1010 – Pharmaceutical Chemistry, Part II (discontinued).
- 9 credits overlap with KJM1111 – Organic Chemistry I.
- 9 credits overlap with KJM1110 – Organic chemistry I (continued).
Teaching
Lectures and student-activating teaching activities, including flipped classroom, laboratory work and student led colloquiums.?
- 1 hour compulsory introductory lecture
- 30 hours of lectures
- 10 hours of flipped classroom
- 22 hours of student led colloquiums - 50 % compulsory attendance
- 35 hours of laboratory work (5 exercises of up to 7 hours duration, with submission of a laboratory report for each exercise) - compulsory
- 5 hours laboratory lectures with an introduction to laboratory work/hazard aspects/health, safety, and environment (HSE) - compulsory
Compulsory participation in the course must be completed and compulsory submissions must be approved in order to take the exam.