FARM1100 – Pharmaceutical Chemistry
Course description
Schedule, syllabus and examination date
Course content
FARM1100 provides pharmacy students with a solid foundation in basic chemistry. Special emphasis is placed on the parts of general chemistry that are relevant to pharmacy. The course also provides an? introduction to basic organic chemistry, focusing on key functional groups and their physicochemical properties. Drug-related examples and issues are consistently used throughout the teaching to contextualize the various topics within a pharmaceutical perspective. The course provides the necessary foundation for students to follow other pharmaceutical subjects taught later in the pharmacy program, ensuring that their pharmaceutical knowledge has a molecular basis. FARM1100 is based on Chemistry 2 from Norwegian high school.
Learning outcome
After completing the course, you will be able to:
- describe the structural and bonding relationships in drug substances, as well as explain how this gives rise to their geometry and intermolecular forces.
- describe the general physical properties of gases, liquids, solids, and solutions, and explain how the melting and boiling points of chemical compounds are affected by intermolecular forces, pressure, and the presence of impurities.
- perform calculations to prepare buffers and solutions of drug substances.
- perform pH calculations and assess how changes in chemical structure can affect the acid-base properties of drug substances.
- evaluate the solubility of drug substances and apply knowledge of functional group acid-base properties to assess how pH changes affect the solubility of drug substances.
- apply knowledge of chemical equilibria, acid-base equilibria, and solubility equilibria to assess and calculate how pharmaceutically relevant equilibria will be affected by changes.
- apply knowledge of chemical kinetics to perform pharmacy-relevant calculations within reaction kinetics.
- explain the relationship between fundamental thermodynamic quantities and the spontaneity of chemical reactions.
- account for central radioactive processes and substances within radiopharmacy.
- apply selected pharmacy-relevant chemical laboratory methods, interpret and communicate results of chemical experiments in writing, and convey professional information to fellow students.
Admission to the course
The course is only available to students enrolled at the Department of Pharmacy at the University of Oslo.
Pregnant and breastfeeding:?For safety reasons, pregnant and breastfeeding women are not allowed to participate in this course. This is because chemicals used in the laboratory exercises can be harmful to the fetus/child. Exemption or facilitation of the laboratory exercises will not be granted, as these are necessary to meet the learning outcomes of the course.
Formal prerequisite knowledge
The admission requirements for the 5-year Master`s Programme in Pharmacy.
Health, safety and the environment (HSE):?There are compulsory HSE courses at the beginning of the first semester. For students who start at the 5-year Master`s Programme in Pharmacy, the following HSE courses are required HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety.
If you fail to pass the HSE courses within the set deadlines you will not be allowed to continue the study programme until the courses are passed, i.e. the following year at the earliest.
Course exemption:?Laws and regulations describing the overall learning outcome regulate the Pharmacy programme. Exemptions are only granted if all learning outcomes in the course are covered.
Recommended previous knowledge
The course builds on Kjemi 2 from Norwegian high school.
Overlapping courses
- 9 credits overlap with FRM1000 – Pharmaceutical Chemistry, Part I (discontinued).
- 7 credits overlap with KJM1100 – General chemistry (continued).
- 7 credits overlap with KJM1101 – Generell kjemi.
- 7 credits overlap with KJM1002 – Introduction to Chemistry.
- 4 credits overlap with KJM1001 – Introduction to chemistry (continued).
Teaching
Lectures, flipped classroom, colloquiums and laboratory exercises.?
- 30 hours of lectures
- 12 hours of flipped classroom
- 20 hours of student-active colloquia (50 % compulsory attendance)
- 30 hours of laboratory work (five laboratory exercises and submission of five laboratory journals) - compulsory
- 5 hours laboratory lectures - compulsory
In order to participate in laboratory exercises, it is a requirement that the HSE course HMS0503 – Laboratory Safety must be passed.
Compulsory participation in the course must be completed and compulsory submissions must be approved to pass the exam.?Read more about what applies in the event of absence from compulsory activities.
As?the?teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance.?Read about your insurance cover as a student.
Access to teaching:?A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.
Completed and approved compulsory coursework are valid for 3 years.
Examination
Final written exam which counts 100?% towards the final?grade.?
Requirement for taking the exam:
- The five laboratory exercises must be conducted, and the five associated laboratory lectures must be attended.
- The five laboratory journals must be approved within the given deadlines.
- Approved 50 % attendance in the colloquia.
Withdrawal from an examination:?It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt.
It will also be counted as one of three?attempts to sit the exam for this course, if you sit the exam for one of the following courses:
- FRM1000 – Pharmaceutical Chemistry, Part I (discontinued)
- KJM1100 – General chemistry (continued)
- KJM1101 – Generell kjemi
- KJM1002 – Introduction to Chemistry
Examination support material
Casio FX-991EX calculators are handed out to all exam candidates at the beginning of the exam. You may not use your own calculator on the exam. The students are themselves responsible for making themselves familiar with the calculator that is handed out at the exam.
The periodic table and the formula collection for the course will be digitally available at the exam.
Language of examination
The examination text is given in Norwegian. You may submit your response in Norwegian, Swedish or Danish.
Grading scale
Grades are awarded on a scale from A to F, where A is the best grade and F is a fail. Read more about the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more:
More about examinations at UiO
- Use of sources and citations
- Special exam arrangements due to individual needs
- Withdrawal from an exam
- Illness at exams / postponed exams
- Explanation of grades and appeals
- Resitting an exam
- Cheating/attempted cheating
You will find further guides and resources at the web page on examinations at UiO.