Within the Earth Biogenome Norway initiative (EBP-Nor) we have generated quite a few high quality (chromosome length) genome assemblies of birds (and other vertebrates). Birds have several features associated with their genomes that are very fascinating – including quite conserved chromosome structure (for some chromosomes), genome size is also conserved (for many species) and they have mini-chromosomes. In addition, many species have strong sexual dimorphisms (which have a sex chromosome origin) and peculiar behavioral differences (within and between species). The behavioral and morphological differences within one and the same species have been shown to be associated with chromosomal inversions. As part of the EBP-Nor effort to sequence all eukaryotic species in Norway we have generated annotated genome assembles for several passerine birds, seabirds and ducks as well as the Norwegian national bird, the white throated dipper (fossekall; Cinclus cinclus). Additional species are underway.
We are seeking two master students: One master student will study differences in chromosome structure and gene synteny in a phylogenetic context. Furthermore, the student is expected to study gene content and the nature of mini-chromosomes in some selected birds (for which we have the best assemblies). Questions that are asked include are the mini-chromosomes real or an artifact of incomplete assembly, and if real, which genes are found in mini-chromosomes and are they expressed and inherited in a Mendelian fashion? This project may involve both bioinformatics and lab work – and if time allows population sampling and analyses. The master student will contribute to and collaborate with a large network of scientists at CEES but also across Norway and internationally.
The second master student will compile a list of sexually dimorphic species and examine their genome assemblies to see whether sexual chromosomes have an enrichment of genes associated with mating system evolution, sperm characteristics, or sexual traits (plumage coloration). This study will leverage the high-quality genome assemblies available for several bird species and will involve a combination of bioinformatics. The student will work collaboratively with a large network of scientists at the CEES, and the Natural History Museum at UiO.
What you will learn: You will learn bioinformatics and evolutionary genomics. By using cutting-edge bioinformatic techniques you’ll be able to get job offers within (PhD) and outside academia on programing and bioinformatics.
What we offer: We offer a friendly and kind mentoring environment, membership in ForBio research school (the research school in biosystematics) where you will be able to take courses in several places in Norway. You will potentially be able to attend international courses if they fit with the objectives, and in a national conference (ForBio meeting).
Supervisors: Kjetill S Jakobsen and José Cerca