MF9330 – Glycobiology
Course description
Course content
The course focuses on different glycoconjugates in the body, such as glycolipids, glycoproteins and proteoglycans. One major focus will be on the connection between structure and function. The glycoconjugates in the body have a series of important functions in relation to regulation of inflammatory reactions, filtering in the kidneys, wound healing, development of atherosclerosis etc. One part of the course will be on the relationship between glycobiology and diet related diseases such as diabetes and coronary heart disease.
Learning outcome
The course will provide insight into the structure and biological functions of
Glycoproteins
Glycolipids
Proteoglycans
In the course papers from front line research will be used to address:
Regulation of the synthesis of glycoconjugates
Turnover and degradation of glycoconjugates
Glycoconjugates and intracellular signaling systems
How diabetic hyperglycemia changes these processes and contributes in pathogenesis
The molecular biological basis for how glycoconjugates affect atherogenesis
Glycoconjugates and joint diseases
Glycoconjugates and lysosomal storage diseases
Glycoconjugates and Alzheimer’s disease
Admission
Ph.D. candidates and students at the Medical Student Research Programme will get first priority to the course.
Prerequisites
Formal prerequisite knowledge
Master degree or equivalent in human biology, physiology, cell biology, biochemistry, nutrition
Recommended previous knowledge
Master degree or equivalent in molecular biology, signal transduction
Teaching
The teaching includes lectures, group work, student presentations, discussions and home assignments.
NB! You have to participate in at least 80 % of the teaching to be allowed to take the exam. Attendance at lectures will be registered.
Examination
To pass exam:
Two paper presentations
One written task (5 pages) also to be presented orally
One final exam task (minimum 10 pages) to be evaluated by external sensor
Grading: pass/fail.
Explanations and appeals
Evaluation
The course is subject to continuous evaluation. At regular intervals we also ask students to participate in a more comprehensive evaluation.