The course is held at Domus Medica (DM), Sognsvannsveien 9.
Teachers:
Associate prof. Jon Michael Gran (course leader), Department of Biostatistics, IMB.
Associate prof. Kjetil R?ysland, Department of Biostatistics, IMB.
Teaching facilities:
Lectures take place in auditoriums Nye auditorium 13, Lille Auditorium and Runde Auditorium at DM. Registration and computer labs take place at other locations as noted in the program.
Literature:
It is recommended to buy one of the following two books:
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B. R. Kirkwood and J. A. C. Sterne: Essential medical statistics, 2nd ed. Blackwell, 2003.
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In Norwegian: O. O. Aalen et al: Statistiske metoder i medisin og helsefag. Gyldendal, 2006.
Participants can also consider the following book, which also cover the topics in many other PhD courses in statistics (chapter 1-5 and 11 is most relevant for this course):
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Veier?d MB, Lydersen S, Laake P (eds.): Medical statistics in clinical and epidemiological research. Gyldendal akademisk, 2012 (www.medicalstatistics.no).
All exercises used in the course can be found in a separate exercise booklet, available on Fronter.
Program
Monday May 30th:
Auditorium: Nye auditorium 13, DM
08.30-09.00: Registration. Location: Reception at DM (by the main entrance).
09.00-11.45: Data and descriptive statistics (Gran). Litterature: Aalen kap. 1 og 2, K&S kap 2, 3 og 4.
11.45-12.30: Lunch
12.30-13.45: Exercise 1 and 2 in the exercise booklet. Introduction to SPSS (Gran, R?ysland). Location: Computer room 2nd floor DM/Computer room R-211 DM (new building).
14.00-15.30: Basic concepts of probability (R?ysland). Literature: Aalen chap. 3.1-3.7, K&S chap. 14.
Tuesday May 31st:
Auditorium: Lille auditorium, DM
08.30-10.00: Bayes law. Sensitivity and specificity (R?ysland). Literature: Aalen kap. 3.9 and 3.10, K&S chap. 33.
10.15-10.45: Binomial distribution (R?ysland). Literature: Aalen chap. 4, K&S chap. 15.
11.00-11.45: Exercise 9 and 12 in the exercise booklet (R?ysland).
11.45-12.00: Joint discussion of exercises (R?ysland).
12.00-12.45: Lunch
12.45-14.00: Normal distribution (Gran). Literature: Aalen chap. 5, K&S chap. 5.
14.15-15.00: Exercise 14 in the exercise booklet (Gran).
15.00-15.30: Joint discussion of exercises (Gran).
Wednesday June 1st:
Auditorium: Runde auditorim R-105, DM tilbygg
08.30-10.15: Introduction to hypothesis testing and confidence intervals. One-sample Student’s test and confidence intervals. (Gran). Literature: Aalen chap. 8.1-8.5, K&S chap. 6, 8.
10.30-11.15: Exercise 13 in the exercise booklet (Gran, R?ysland). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
11.30-11.45: Joint discussion of exercises (Gran).
11.45-12.30: Lunch
12.30-14.15: Two sample Student’s test and confidence interval (Gran). Literature: Aalen chap. 8.6 and 8.7, K&S chap. 7.
14.30-15.30: Exercise 15 in the exercise booklet (Gran, R?ysland). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
Thursday June 2nd:
Auditorium: Nye auditorium 13, DM
08.30-10.30: Analysis of proportions (Gran). Literature: Aalen chap. 6.1-6.4, K&S chap. 15, 16.
10.45-11.30: Exercise 16 and 17 in the exercise booklet (Gran).
11.30-11.45: Joint discussion of exercises (Gran).
11.45-12.30: Lunch
12.30-14.15: Analyzing tables (chi squared and exact tests). (Gran). Literature: Aalen chap. 6.5, K&S chap. 17.
14.30-15.30: Exercise 10.1a, 10.3 and 10.7 from Altman, found in the back of the exercise booklet (Gran, R?ysland). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
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Exercises for the intervening period:
You should read through the material from the first period and do the following exercises: 8, 10 and 11 in the exercise booklet.
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Monday June 13th:
Auditorium: Nye auditorium 13, DM
08.30-09.15: Joint discussion of the exercises from the intervening period (Gran).
09.15-11.00: Transformations. Non-parametric methods (Gran). Literature: Aalen chap. 8.8, K&S chap. 13, 30.
11.15-12.15: Exercise 4, and Altman exercise 9.2 and 9.4, from the exercise booklet (Gran, R?ysland). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
12.15-13.00: Lunch
13.00-14.30: Regression analysis, correlation (R?ysland). Literature: Aalen chap. 11.1-11.3, K&S chap. 10.
14.45-15.30: Exercise 3 and 7 in the exercise booklet (R?ysland, Gran). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
Tuesday June 14th:
Auditorium: Nye auditorium 13, DM
08.30-10.30: Regression analysis. Dummy variables, confounding, multiple regression (R?ysland). Literature: Aalen chap. 11.4-11.6, K&S chap. 11 and 12.
10.45-11.45: Exercise 11.2 and 18 in the exercise booklet (R?ysland, Gran). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
11.45-12.30: Lunch
12.30-13.00: Joint discussion of exercises (R?ysland).
13.15-14.30: Multiple regression cont. Interactions (R?ysland). Literature: K&S kap 11, 12.
14.45-15.30: Exercise 27 and 28 in the exercise booklet (R?ysland, Gran). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
Wednesday June 15th:
Auditorium: Nye auditorium 13, DM
08.30-10.45: Logistic regression (R?ysland). Literature: Aalen chap. 12, K&S chap. 19 and 20.
11.00-12.15: Exercise 31 and 32 in the exercise booklet (R?ysland, Gran). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
12.15-13.00: Lunch
13.00-14.15: Sample size and power (Gran). Literature: Aalen chap. 9.6, K&S chap. 35.
14.30-15.30: Exercise 19 in the exercise booklet (Gran).
Thursday June 16th:
Auditorium: Nye auditorium 13, DM
08.30-11.30: Epidemiologic design and basic concepts. Principles for organizing clinical trials. (R?ysland). Literature: Aalen chap. 10, K&S chap. 34.
Literature: Aalen chap. 9, K&S chap. 34.
11.30-12.15: Lunch
12.15-13.15: Survival analysis (Gran). Literature: Aalen chap. 13, K&S chap. 26.
13.30-14.30: Exercise 5 and 6 in the exercise booklet (Gran, R?ysland). Location: Computer room 2nd floor DM/ Computer room R-211 DM (new building).
14.45-15.15: Summary (Gran).