Teaching facilities:
The course takes place in Rikshospitalet, Domus Medica (DM) and Domus Odontologica (DO) at the University of Oslo.
Exercises will be held in PC-rooms. Detailed information can be found in the program below.
Teachers:
Professor Odd O. Aalen, Department of Biostatistics, IMB (Responsible for the course)
Associate professor Bettina Kulle Andreassen, Epi-gen, Ahus, UiO
Associate professor Tron Anders Moger, Department of Biostatistics, IMB
Researcher Milada C. Sm?stuen, OUS and UiO
Research Fellow Morten Valberg, Department of Biostatistics, IMB
Research Fellow ?ystein S?rensen, Department of Biostatistics, IMB
Monday 15. September:
08.30-09.00: Registration. (Outside Lille Auditorium in Domus Medica)
09.00-11.15: Data and descriptive statistics. (Aalen) - Rikshospitalet B1: Gr?nt Aud 1 RH
Literature: Aalen chap. 1 og 2, Kirkwood and Sterne chap. 3 and 4
11.30-12.45: Exercises: Introduction to SPSS. PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
Exercises: 1 and 2 in the exercise booklet (S?rensen, Aalen)
12.45-13.45: Lunch break
13.45-15.45: Basic concepts of probability. (Aalen) - Nye auditorium 13, DM
Literature: Aalen chap. 3.1-3.7. Kirkwood and Sterne chap. 14
Tuesday 16. September:
Runde auditorium R-105, DM tilbygg
08.30-09.15: Bayes law. Sensitivity, specificity. (Aalen).
Literature: Aalen chap. 3.9 and 3.10, Kirkwood and Sterne chap. 36.2
09.30-11.00: Binomial distribution. (Aalen).
Literature: Aalen chap. 4, Kirkwood and Sterne section 15.1 and 15.2
11.15-12.15: Exercises: 9 and 12 in the exercise booklet. (Aalen)
12.15-13.15: Lunch break
13.15-14.00: The normal distribution. (Andreassen). Literature: Aalen chap. 5, Kirkwood and Sterne chap. 5
14.15-15.00: Exercises. Exercise 14 in the exercise booklet. (Andreassen)
15.15-15.45: Discussion of exercises. (Andreassen)
Wednesday 17. September:
08.30-10.45: Introduction to hypothesis testing and confidence intervals. One-sample Student’s test and conf. interval. (Andreassen). – Store auditorium A1.1001, DO
Literature: Aalen chap. 8.1-8.5, Kirkwood and Sterne chap. 4, 6 and 7
11.00-12.00: Exercises. Exercise 13 in the exercise booklet. (Andreassen, Aalen) - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
12.00-12.45: Lunch break
12.45-14.15: Two sample Student’s test and confidence interval. (Andreassen). - Lille auditorium A1.1004, DO
14.15-15.45: Exercises. Exercise 15 in the exercise booklet. (Andreassen, S?rensen). - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
Thursday 18. September:
08.30-11.15: Transformations. Non-parametric methods. (Aalen). - Runde auditorium R-105, DM tilbygg
Literature: Aalen chap. 8.8, Kirkwood and Sterne chap. 13 and 30.2
11.15-12.15: Exercises. Altman 9.2 and 9.4 and exercise 4 (all in the booklet). (Stensrud, Aalen) - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
12.15-13.00: Lunch break
13.00-14.30: Regression analysis, correlation. (Aalen) - Runde auditorium R-105, DM tilbygg
Literature: Aalen chap. 11.1-11.3, Kirkwood and Sterne chap. 10
14.45-15.45: Exercises. (Stensrud, Aalen)
3 and 7 in the exercise booklet - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
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Exercises for the intervening period:
You should read through the material from the first period and do the following exercises:
8, 10 and 11 in the exercise booklet
We shall go through the exercises at the beginning of the next period.
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Monday 29. September:
08.30-09.30: Discussion of the exercises from the intervening period. (Aalen) - Store auditorium A1.1001, DO
09.45-11.15: Regression analysis cont., multiple regression. (Aalen) - Store auditorium A1.1001, DO
Literature: Aalen chap. 11.4-11.6, Kirkwood and Sterne chap. 11 and 12
11.30-12.30: Exercises. (Stensrud, Aalen) - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
Exercises: Altman 11.2 + 18 in exercise booklet.
12.30-13.15: Lunch break
13.15-15.00: Some more about regression. Confounding. Interaction. (Aalen) - Nye auditorium 13, DM
Literature: Kirkwood and Sterne chap. 38
Tuesday 30. September:
Store auditorium A1.1001, DO
08.30-09.30: Epidemiologic design and basic concepts. (Aalen)
09.45-11.30: Principles for organizing clinical trials. (Aalen)
Literature: Aalen chap. 9 og 10, Kirkwood and Sterne chap. 32 and 34
11.30-12.15: Lunch break
12.15-14.00: Statistical analysis of proportions. Odds ratio, relative risk etc. (Valberg)
Literature: Aalen chap. 6.1-6.4, Kirkwood and Sterne chap. 15 and 16
14.15-15.15: Exercises. (Valberg)
Exercises 16 and 17 in the booklet
15.15-15.45: Discussion of exercises (Valberg)
Wednesday 1. October:
08.30-10.15: Analyzing tables (chi squared, exact and Monte Carlo tests) (Valberg) - Store auditorium A1.1001, DO
Literature: Aalen chap. 6.5, Kirkwood and Sterne chap. 17
10.30-11.30: Exercises. (Valberg, S?rensen) - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
Exercises: Altman 10.1a, 10.3, 10.7 (see Exercise booklet).
11.30-12.15: Lunch break
12.15-14.30: Logistic regression (Moger) - Store auditorium A1.1001, DO
Literature: Aalen Chap. 12, Kirkwood and Sterne, Chap. 19, 20.
14.45-15.45: Exercise 23 in the booklet (Moger, S?rensen) - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
Thursday 2. October:
08.30-09.45: Sample size and power. (Stensrud).- Store auditorium A1.1001, DO
Literature: Aalen chap. 9.6, Kirkwood and Sterne kap. 35
10.00-11.00: Exercises. (Stensrud) - Store auditorium A1.1001, DO
Exercise 19 from booklet
11.15-12.15: Survival analysis. (Sm?stuen) - Store auditorium A1.1001, DO
Literature: Aalen chap. 13, Kirkwood and Sterne chap. 26
12.15-13.00: Lunch break
13.00-13.45: Survival analysis cont. (Sm?stuen) - Store auditorium A1.1001, DO
14.00-15.15: Exercises with discussion. (Stensrud, Sm?stuen) - PC-stue 2. Etasje DM/ PC-stue R-211 DM tilbygg
Exercises 5 and 6 from booklet
15.30-15.45: Summary. (Sm?stuen) - Store auditorium A1.1001, DO
Course exam:
A take home exam will be handed out at the end of the course. This should be solved at home and then returned within a specified deadline.