Program 2.9.- 19.9.2013

Teaching facilities:

The course takes place in Domus Medica (DM) and Domus Odontologica (DO) at the University of Oslo.

All the lectures will be held at A1.1001 store auditorium, Domus Odontologica.

Exercises will be held in PC-rooms. Detailed information can be found in the program below.

Teachers:

Professor Odd O. Aalen, Department of Biostatistics, IMB (Responsible for the course)
Associate professor Bettina Kulle Andreassen, Epi-gen, Ahus, UiO
Postdoc Jon Michael Gran, Department of Biostatistics, IMB
Associate professor Tron Anders Moger, Department of Biostatistics, IMB
Research Fellow Morten Valberg, Department of Biostatistics, IMB

Monday 2. September:

08.30-09.00: Registration. (Outside Lille Auditorium in Domus Medica)
09.00-11.15: Data and descriptive statistics.  (Aalen).
Literature: Aalen chap. 1 og 2,  Kirkwood and Sterne chap. 3 and 4
11.30-12.45: Exercises: Introduction to SPSS. - GA21 R-211 PC-stue DM tilbygg/ GA02 A1.1022 Datarom, DO
Exercises: 1 and 2 in the exercise booklet (Aalen, Gran)
12.45-13.45: Lunch break
13.45-15.45: Basic concepts of probability. (Aalen).
 Literature: Aalen chap. 3.1-3.7. Kirkwood and Sterne chap. 14

Tuesday 3. September:

08.30-09.15: Bayes law. Sensitivity, specificity. (Aalen).
Literature: Aalen chap. 3.9 and 3.10,  Kirkwood and Sterne chap. 36.2
09.30-11.00: Binomial distribution. (Aalen).
Literature: Aalen chap. 4, Kirkwood and Sterne section 15.1 and 15.2
11.15-12.15: Exercises: 9 and 12 in the exercise booklet. (Aalen)
12.15-13.15: Lunch break
13.15-14.00: The normal distribution. (Andreassen).
 Literature: Aalen chap. 5, Kirkwood and Sterne chap. 5
14.15-15.00: Exercises. Exercise 14 in the exercise booklet.
(Andreassen)
15.15-15.45: Discussion of exercises. (Andreassen)

Wednesday 4. September:

08.30-10.45: Introduction to hypothesis testing and confidence intervals. One-sample Student’s test and conf. interval. (Andreassen).
Literature: Aalen chap. 8.1-8.5, Kirkwood and Sterne chap. 4, 6 and 7
11.00-12.00: Exercises. Exercise 13 in the exercise booklet. (Andreassen, Aalen) - GA21 R-211 PC-stue DM tilbygg/ GA01 2170B PC-stue 2. et, DM
12.00-12.45: Lunch break
12.45-14.15: Two sample Student’s test and confidence interval. (Andreassen).
Literature: Aalen chap. 8.6 og 8.7, Kirkwood and Sterne chap. 7
14.15-15.45: Exercises. Exercise 15 in the exercise booklet. (Andreassen, Aalen). - GA21 R-211 PC-stue DM tilbygg/ GA01 2170B PC-stue 2. et, DM
 

Thursday 5. September:

08.30-11.15: Transformations. Non-parametric methods. (Aalen).
Literature: Aalen chap. 8.8, Kirkwood and Sterne chap. 13 and 30.2
11.15-12.15: Exercises. Altman 9.2 and 9.4 and exercise 4 (all in the booklet). (Gran, Aalen)- GA21 R-211 PC-stue DM tilbygg/ GA02 A1.1022 Datarom, DO
12.15-13.00: Lunch break
13.00-14.30: Regression analysis, correlation. (Aalen).
Literature: Aalen chap. 11.1-11.3, Kirkwood and Sterne chap. 10
14.45-15.45: Exercises. (Gran, Aalen)
3 and 7 in the exercise booklet - GA21 R-211 PC-stue DM tilbygg/ GA02 A1.1022 Datarom, DO
            
      _________________

Exercises for the intervening period:

You should read through the material from the first period and do the following exercises:
8, 10 and 11 in the exercise booklet
We shall go through the exercises at the beginning of the next period.

                  _________________

Monday 16. September:

08.30-09.30: Discussion of the exercises from the intervening period. (Aalen)
09.45-11.15: Regression analysis cont., multiple regression. (Aalen).
Literature: Aalen chap. 11.4-11.6, Kirkwood and Sterne chap. 11 and 12
11.30-12.30: Exercises. (Gran, Aalen) - GA21 R-211 PC-stue DM tilbygg/ GA01 2170B PC-stue 2. et, DM
Exercises: Altman 11.2 + 18 in exercise booklet.
12.30-13.15: Lunch break
13.15-15.00: Some more about regression. Confounding. Interaction. (Aalen)
Literature: Kirkwood and Sterne chap. 38

Tuesday 17. September:

08.30-09.30: Epidemiologic design and basic concepts. (Aalen)
09.45-11.30: Principles for organizing clinical trials. (Aalen).
Literature: Aalen chap. 9 og 10, Kirkwood and Sterne chap. 32 and 34
11.30-12.15: Lunch break
12.15-14.00: Statistical analysis of proportions. Odds ratio, relative risk etc. (Valberg).
Literature: Aalen chap. 6.1-6.4, Kirkwood and Sterne chap. 15 and 16
14.15-15.15: Exercises. (Valberg).
Exercises 16 and 17 in the booklet
15.15-15.45:  Discussion of exercises.

Wednesday 18. September:

08.30-10.15: Analyzing tables (chi squared, exact and Monte Carlo tests) (Valberg)
Literature: Aalen chap. 6.5, Kirkwood and Sterne chap. 17
10.30-11.30: Exercises. (Valberg, Aalen) - GA21 R-211 PC-stue DM tilbygg/ GA01 2170B PC-stue 2. et, DM
Exercises: Altman 10.1a, 10.3, 10.7 (see Exercise booklet).
11.30-12.15: Lunch break
12.15-14.30: Logistic regression (Moger)
Literature: Aalen Chap. 12, Kirkwood and Sterne, Chap. 19, 20.
14.45-15.45:  Exercise 23 in the booklet (Moger, Aalen) - GA21 R-211 PC-stue DM tilbygg/ GA01 2170B PC-stue 2. et, DM
 

Thursday 19. September:

08.30-09.45: Sample size and power. (Gran).
Literature: Aalen chap. 9.6, Kirkwood and Sterne kap. 35
10.00-11.00: Exercises. (Gran)
Exercise 19 from booklet
11.15-12.15: Survival analysis. (Gran).
Literature: Aalen chap. 13, Kirkwood and Sterne chap. 26
12.15-13.00: Lunch break
13.00-13.45: Survival analysis cont. (Gran).
14.00-15.15: Exercises with discussion. (Gran, Aalen) - GA21 R-211 PC-stue DM tilbygg/ GA01 2170B PC-stue 2. et, DM
Exercises 5 and 6 from booklet
15.30-15.45: Summary. (Gran)

Course exam:

A take home exam will be handed out at the end of the course. This should be solved at home and then returned within a specified deadline.

Published June 12, 2013 2:45 PM - Last modified June 14, 2013 9:36 AM