In today's lecture, I derived ¡­

In today's lecture, I derived the ODE that models the dynamics of protein production, regulated by a single transcription factor, using the separation of time scales. Explicit solutions were derived and biologically relevant metrics such as the steady state protein expression level and response time characterized. The response time was shown to be similar to the cell cycle life time. Most of the material was from Chap 2 of Alon's book.

In the next lecture, i will start with some modeling exercises from chap 2 of Alon's book. Next, we will see how self regulation arises as a network motif and how it can increase robustness and speed up response time.