Joachim Mossige

Image of Joachim Mossige
Norwegian version of this page
Mobile phone +4792233276
Room RITMO: Red Room / Physics Dept.: v402
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Visiting address 澳门葡京手机版app下载sveien 3A Harald Schjelderups hus 0373 Oslo / Dept. Physics Sem S?lands vei 24 0371 Oslo
Postal address Postboks 1133 Blindern 0318 Oslo

Bio

Joachim received his Ph.D. in microfluidics from the University of Oslo and was a postdoc at Stanford and at UCSB to learn about interfacial flows and miscible fluids. He then worked as a teacher of fluid mechanics at the Norwegian University of Life Sciences, and developed "kitchen flows" as an affordable and accessible learning strategy. Back at the University of Oslo, he now works in a multi-disciplinary team to unravel how cells work in concert to form organs. Applications of his research span from water treatment to contact lens development and drug sensitivity testing.

Image may contain: Product, Font, Line, Drinkware, Diagram.
Overview of Joachim's main expertise in experimental fluid dynamics and soft matter physics: (a) microfluidics (b) miscible flows (c) kitchen flows (d) interfacial dynamics. Part (a) adapted from Mossige et al., PRApplied 2018. Part (b) adapted from Mossige et al., Phys. Fluids 2021. Part (c) adapted from Mossige et al., Rev. Mod. Phys. 2023. Image courtesy of Sam Dehaeck. Part (d) adapted from Chandran Suja and Mossige et al. J. Colloid Interface Sci. 2022.

Utilizing light-sheet microscopy

As postdoc in the UiO:LifeScience ITOM-project, Joachim built his own light-sheet microscope to characterize how early mammalian embryo models (using so-called mouse gastruloids) grow and develop, and how the first organs form. Especially, he is interested in how cells self-organize and orchestrate their motion to form tissue. To explain the underpinning dynamics, he couples his experiments with 3D simulations.

3d rendered image of a 5 day old (cardiovascular) mouse gastruloid. The interior structures are primitive gut cells (endoderm germ layer). MP1 cell line with Sox17 RFP (endoderm) and T/Bra GFP (mesoderm) reporters. Sample provided by Sergei Ponomartcev. Fused, deconvolved and rendered in Huygens SVI.
Optical sectioning through the anterior part of a 5 day old mouse (cardiovascular) gastruloid. The bright regions are primitive gut cells (endoderm germ layer). Made from MP1 cell line with Sox17 RFP (endoderm) and T/Bra GFP (mesoderm) reporters. Sample provided by Sergei Ponomartcev. Fused, deconvolved and rendered in Huygens SVI.

To fully utilize light-sheet imaging, Joachim also studies collective cell migration and how nerve cells make new connections in live zebrafish with members of the Camila Esguerra Group and he studies the cells' own recycling system (autophagy) in Drosophila embryos in collaboration with the Helene Kn?velsrud's group. 

3D rendered image showing how cells invade the brain of a zebrafish larvae (6 dpf). The green signal shows the blood vessels, and the red signal shows the cells. To produce this visualization, image stacks from different angles were fused and deconvolved in Huygens SVI and rendered in Imaris. Samples provided by Wietske van der Ent, Camila Esguerra Group - Chemical Neuroscience, UiO. 
Schematic overview of our home-built light-sheet microscope.

Collaborators 

Dag K. Dysthe (Dept. Physics) oversees the experimental investigation, and Xian Hu helps out with 3D rendering. To explain the dynamics of collective cell migration, Dr. Richard Ho from Luiza Angheluta-Bauer's group conducts complementary simulations. Postdocs Sergei Ponomartcev and Nathalia Smirnova from Hybrid Technology Hub SFF provide stained gastruloid samples. Steven Ray Haakon Wilson at the Chemistry Department contributes with important mass spectrometry measurements. Joachim reports to the center director at RITMO SFF Alexander Refsum Jensenius

Funding

The ITOM project is funded by UiO:Life Science.

Other interests

Joachim is an avid climber and a hobby jazz musician.

Courses Taught

Certificate

Mentoring experience

Academic positions held

  • 2022:          University lecturer at the Norwegian University of Life Sciences
  • 2020-2021: Postdoctoral fellow in Todd Squires' group at UC Santa Barbara
  • 2018-2020: Postdoctoral fellow in Gerry Fuller's group at Stanford University
  • 2013-2017: Ph.D. student in Atle Jensen's group at the University of Oslo

 

Tags: Life Science, Condensed matter physics, Soft matter, Tissue mechanics, Fluid mechanics, teaching and learning in science

Publications

Culinary fluid mechanics and other currents in food scienceRev. Mod. Phys. 95, 025004 (2023)

Innovations in fluid mechanics have been leading to better food since ancient history, while creativity in cooking has inspired fundamental breakthroughs in science. This review addresses how recent advances in hydrodynamics are changing food science and the culinary arts and, reciprocally, how the surprising phenomena that arise in the kitchen are leading to new discoveries across the disciplines, including molecular gastronomy, rheology, soft matter, biophysics, medicine, and nanotechnology. This review is structured like a menu, where each course highlights different aspects of culinary fluid mechanics. Our main themes include multiphase flows, complex fluids, thermal convection, hydrodynamic instabilities, viscous flows, granular matter, porous media, percolation, chaotic advection, interfacial phenomena, and turbulence. For every topic, an introduction and its connections to food are provided, followed by a discussion of how science could be made more accessible and inclusive. The state-of-the-art knowledge is then assessed, the open problems, along with the likely directions for future research and indeed future dishes. New ideas in science and gastronomy are growing rapidly side by side.

An evaporating cocktail
From Mossige et al., Rev. Mod. Phys 2023. Image courtesy of Sam Dehaeck. 

 

 

 

 

 

 

 

 

Dewetting characteristics of contact lenses coated with wetting agents - J. Colloid Interface Sci.614, 24-32.

Contact lenses alter tear film stability due to the differences in surface properties as compared to the mucus layer of the eye. We characterize the effect of different surface coatings on the thin-film stability by using a dynamic thin-film interferometer developed in the Fuller group. We reveal that despite the wide variations in wetting agent molecular properties like charge and polarity, the time to dewet 50% of the contact lens linearly scales with the product of the receding contact angle (θr) and the contact angle hysteresis (cos θr ?cos θa). A corollary of this finding is the importance of minimizing contact angle hysteresis for effective wetting performance. Overall, we believe the methodology and results from this study provides a basis for identifying optimal wetting agents to minimize tear film dewetting and maximize patient comfort.

My main contribution to this project was conducting optical thin film interferometry experiments and reporting the obtained drainage and dewetting results directly to the scientific investigators at Johnson and Johnson, who sponsored this joint investigation. In addition, I mentored and trained one high school intern and one undergraduate student in Chemical Engineering at Stanford; the latter person is co-author on our paper. 

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  • Nigards?y, Bj?rg Synn?ve; Nilsen, Vegard; Karlsen, Tom A. & Mossige, Joachim (2023). Characterization of particle removal in an airlift pump with a U-bend. Physics of Fluids. ISSN 1070-6631. 35(7). doi: 10.1063/5.0156131. Full text in Research Archive
  • Mathijssen, Arnold J.T.M.; Lisicki, Maciej; Prakash, Vivek Nagandra & Mossige, Joachim (2023). Culinary fluid mechanics and other currents in food science. Reviews of Modern Physics. ISSN 0034-6861. 95(2). doi: 10.1103/RevModPhys.95.025004.
  • Nigards?y, Bj?rg Synn?ve; Nilsen, Vegard; Karlsen, Tom Arild & Mossige, Joachim (2023). Characterization of particle removal in an airlift pump with a U-bend. arXiv.org. ISSN 2331-8422. doi: 10.48550/arXiv.2302.12655.
  • Nordbotten, Jan Martin & Mossige, Joachim (2023). The dissolution of a miscible drop rising or falling in another liquid at low Reynolds number. Physics of Fluids. ISSN 1070-6631. 35(1). doi: 10.1063/5.0133025. Full text in Research Archive
  • Nordbotten, Jan Martin & Mossige, Joachim (2022). The dissolution of a miscible drop rising or falling in another liquid at low Reynolds number. arXiv. doi: 10.48550/arXiv.2211.01242.
  • Fuller, Gerald G.; Lisicki, Maciej; Mathijssen, Arnold J.T.M.; Pasquino, Rosanna; Prakash, Vivek Nagandra & Mossige, Joachim [Show all 7 contributors for this article] (2022). Kitchen flows: Making science more accessible, affordable, and curiosity driven. Physics of Fluids. ISSN 1070-6631. 34(11). doi: 10.1063/5.0131565. Full text in Research Archive
  • Mathijssen, Arnold JTM; Lisicki, Maciej; Prakash, Vivek N & Mossige, Endre Joachim Lerheim (2022). Culinary fluid mechanics and other currents in food science. arXiv.org. ISSN 2331-8422. Full text in Research Archive
  • Chandran Suja, Vineeth; Verma, Archana; Mossige, Endre Joachim Lerheim; Cui, K.W.; Xia, V. & Zhang, Y. [Show all 9 contributors for this article] (2022). Dewetting characteristics of contact lenses coated with wetting agents. Journal of Colloid and Interface Science. ISSN 0021-9797. doi: 10.1016/j.jcis.2022.01.075.
  • Mossige, Endre Joachim Lerheim; Chandran Suja, Vineeth; Walls, Daniel Joseph & Fuller, Gerald G. (2021). Dynamics of freely suspended drops translating through miscible environments. Physics of Fluids. ISSN 1070-6631. 33. doi: 10.1063/5.0041536.
  • Mossige, Joachim; Chandran Suja, Vineeth; Islamov, Meiirbek; Walls, Daniel Joseph & Fuller, Gerald G. (2020). Evaporation-induced Rayleigh–Taylor instabilities in polymer solutions. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. ISSN 1364-503X. doi: 10.1098/rsta.2019.0533.
  • Mossige, Endre Joachim & Jensen, Atle (2020). Clog-free trilobite filtration: Tunable flow setup and velocity measurements. Micromachines. ISSN 2072-666X. 11(10). doi: 10.3390/mi11100904. Full text in Research Archive
  • Mossige, Endre Joachim; Edvardsen, Bente; Jensen, Atle & Mielnik, Michal Marek (2019). A tunable, microfluidic filter for clog?free concentration and separation of complex algal cells. Microfluidics and Nanofluidics. ISSN 1613-4982. 23(56). doi: 10.1007/s10404-019-2209-y. Full text in Research Archive
  • Mossige, Endre Joachim; Jensen, Atle & Mielnik, Michal Marek (2018). Separation and Concentration without Clogging Using a High-Throughput Tunable Filter. Physical Review Applied. ISSN 2331-7019. 9(5). doi: 10.1103/PhysRevApplied.9.054007. Full text in Research Archive
  • Mossige, Endre Joachim; Jensen, Atle & Mielnik, Michal Marek (2016). An experimental characterization of a tunable separation device. Microfluidics and Nanofluidics. ISSN 1613-4982. 20(12). doi: 10.1007/s10404-016-1826-y.

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  • Gholamipour-Shirazi, Azarmidokht & Mossige, Joachim (2024). Impact of Mixing on Flavor and Aroma Development in Fermented FoodsImpact of Mixing on Flavor and Aroma Development in Fermented Foods. arXiv. doi: 10.48550/arXiv.2412.10190.
  • Vestre, Katharina; Mossige, Joachim; L?vvik, Ole Martin & Jemterud, Torkild (2024). Abels t?rn 12.1.2024. [Radio]. Abels t?rn NRK P2.
  • Mossige, Joachim (2023). The science of nerdy science cakes.
  • Einevoll, Gaute Tomas & Mossige, Joachim (2023). Episode #72: Om kj?kkenfysikk. [Internet]. Podcast "Vett og vitenskap".
  • Roberts, Aubrey Jane; G?rbitz, Carl Henrik; Mossige, Joachim; Samset, Bj?rn Hallvard & Uggerud, Einar (2023). Abels T?rn. [Radio]. NRK P3 EKKO.
  • Mossige, Joachim & Lynnebakken, Hilde (2023). Her foreg?r toppforskning fra kj?kkenet. [Internet]. forskning.no.
  • Mossige, Joachim (2023). Felleskollokvium: Culinary fluid mechanics and other currents in food science.
  • Einevold, Gaute & Mossige, Joachim (2023). Vett og Vitenskap med Gaute Einevold: Om kj?kkenfysikk - med Joachim Mossige. [Internet]. https://vettogvitenskap.no og som Apple podcast.
  • Jemterud, Torkel & Mossige, Joachim (2023). Abels t?rn jubelsending. [Radio]. NRK.
  • Mossige, Joachim (2023). Paneldeltaker p? Abels t?rn.
  • Vogt, Yngve; Krauss, Stefan Johannes Karl; Mossige, Joachim; Dysthe, Dag Kristian; Angheluta, Luiza & Jensenius, Alexander Refsum (2023). Bereder grunnen for kunstige organer. [Business/trade/industry journal]. Apollon.
  • Mossige, Joachim; Combriat, Thomas; J?rstad, Adam Korchan; Grieg, Claudia Emilia; Trondsen, Tiril Kopland & R?set, Erik Joshua [Show all 7 contributors for this article] (2022). LigLivLab's annual presentation: Microfludic Cell Incubator.
  • Mossige, Endre Joachim; Jensen, Atle & Mielnik, Michal Marek (2017). Erratum to: An experimental characterization of a tunable separation device. Microfluidics and Nanofluidics. ISSN 1613-4982. 21(1). doi: 10.1007/s10404-016-1833-z.
  • Mossige, Endre Joachim; Jensen, Atle & Mielnik, Michal Marek (2015). Characterization of the Trilobite Hydrodynamic Particle Separation Microchip with μPIV.

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Published Sep. 5, 2022 11:17 AM - Last modified Dec. 19, 2024 1:37 PM